HUBUNGAN KADAR GLUKOSA DARAH DAN LAMA MENDERITA DIABETES DENGAN DERAJAT RETINOPATI DIABETIKA

Abstract

Background: Diabetic Retinopathy is an important long-standing complication of diabetes mellitus. It is caused by high incidence and it's worse prognosis i.e actuity visual loss. High blood glucose levels (hyperglicemia) and long time endure of diabetic influence the severity of diabetic retinopathy. A long time hyperglycemia enhances changes the cellular component of basalis membranes of retinal cell, immune system, and platelets, therefore the atherosclerosis at the retinal vessels manifested. The objective of the study is to find the relation blood glucose levels and duration endure of diabetic to the severity of Diabetic Retinopathy at Kariadi Hospital Semarang. Methods: The study was analytical using historical study. The data of diabetic patiets with Diabetic Retinopathy as it's complication which found from medical record Kariadi Hospital Semarang during Jan 1st,2002 to Dec 31st,2004. The data include sex, age, blood glucose levels, duration endure of diabetic, and funduscopic examinations, that analysed using logistic regression test. Results: The statistic result were p=0,368 (p> 0,05) for blood glucose levels and p=0,019 (p<0,05) for duration endure of diabetic with CI 95 % or couldn't conclude that high blood glucose related with the severity of Diabetic Retinopathy, but duration endure of diabetic related with the severity of Diabetic Retinopathy. The patients that suffered longtime endure diabetic may occured Proliferative Diabetic Retinopathy. Conclusion: The test could not conclude that blood glucose levels related with the severity of Diabetic Retinopathy but duration endure of diabetic related with the severity of Diabetic Retinopathy.