HUBUNGAN ANTARA TANDA-TANDA GAGAL ORGAN MULTIPEL DENGAN KEMATIAN LANJUT PADA PENDERITA TRAUMA MAYOR (THE RELATIONSHIP BETWEEN SIGNS OF MULTIPLE ORGAN FAILURE AND LATE DEATH ON MAJOR TRAUMA )

WIDIANTONO, WIDIANTONO (2004) HUBUNGAN ANTARA TANDA-TANDA GAGAL ORGAN MULTIPEL DENGAN KEMATIAN LANJUT PADA PENDERITA TRAUMA MAYOR (THE RELATIONSHIP BETWEEN SIGNS OF MULTIPLE ORGAN FAILURE AND LATE DEATH ON MAJOR TRAUMA ). Masters thesis, Program Pendidikan Pasca sarjana Universitas Diponegoro.

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Abstract

Background : It had been recognized trimodal of death due to trauma i.e immediate death, early death and late death. Eighty percent of late death caused by infection and/or multiple organ failure (MOP). The study was aimed to predict late death from signs of MOF. Material and methode : The study was conducted in patients admitted to Kariadi Hospital Semarang during June 2002 - May 2003 with major trauma who met the inclusion criteria, with cohort design Result : There were 84 patients with major trauma,35 from those faced the late death Twenty patients (66,7%) of death cases showed signs of MOF before die. There was significant association between signs of MOF and late death with RR 5,2 ( 95% CI= 1,982-13,646). By Logistic Regression , it was proven that increasing of intracranial pressure as a covariate factor can not be neglected, because association with late death is significant with RR 7,93 (95% CI = 2,490 - 21,823). Conclusion : signs of MOF was significant associated with late death. Latar belakang : Telah diketahui bahwa kematian akibat trauma mengikuti pola trimodal yaitu kematian segera, kematian awal dan kematian lanjut . Delapan puluh persen dari kematian lanjut karena infeksi dan atau gagal organ multipel. Tujuan peneletian adalah memperkirakan kematian lanjut dad tanda-tanda gagal organ miltipel. Bahan dun cam : Penelitian dilakukan terhadap penderita yang datang di Rumah Sakit Kariadi Semarang yang datang pada periode Juni 2002-Mei 2003 dengan trauma mayor yang memenuhi kritreria inklusi. Disain penelitian adalah kohort. Hasil : Tercatat sebanyak 84 penderita dengan trauma mayor, 35 diantaranya mengalami late death. Dua puluh pasien (66,7%) mengalami tanda-tanda gagal organ multipel sebelum kematiannya . Diketahui hubungan yang bennakna antara gagal organ multipel kematian lanjut dengan RR = 5,2 (95% CI = 1,982-13,646). Regresi logistik menunjukkan bahwa faktor peningkatan TIK tidak dapat diabaikan karena dalam analisisnya memberikan RR =7,93 (95% CI = 2,490 - 21, 823). Kesirnpulan : terdapat hubungan antara tanda-tanda gagal organ multipel dengan kematian lanjut.

Item Type:Thesis (Masters)
Subjects:R Medicine > R Medicine (General)
Divisions:Postgraduate Program > Master Program in Biomedical Science
ID Code:12342
Deposited By:Mr UPT Perpus 1
Deposited On:30 May 2010 14:32
Last Modified:30 May 2010 14:32

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