POLA KADAR GLUKOSA DARAH PADA STROKE AKUT

Abstract

Backgrounds: Stroke is a cardiovascular disease that deserves serious attention because it is a common cause of death and it leads to long-term disability. The ideal effort to overcome stroke problem is prevention of risk factors; of the various risk factors, hyperglycemia is an important factor for the occurrence of stroke. Hyperglycemia can occur in patients that do not suffer from or do not have prior history of diabetes mellitus. Purpose: To find out the glucose concentration pattern at one occasion in acute stroke, the correlation of hyperglycemia and length of treatment, mortality, and the number of stroke location affected. Material and Methods: As a prospective cross-sectional study design, the study was performed on patients with acute stroke that were undergoing treatment in the department of neurology at Dr Kariadi Hospital. The data obtained was blood glucose level at one occasion i.e. in day I, III, V, GD I/II, Al C Results: There were 66 patients with acute stroke (based on CT scan): 27 patients with hemorrhage (hemorrhagic stroke), 39 patients without hemorrhage (nonhemorrhagic stroke); 27 males and 39 females, the average age of patients with hemorrhagic stroke was 54.44 +- 11.22 years whereas the average age of patients with nonhemorrhagic stroke was 59.05 +- 11.65 years. The blood glucose level at one occasion increased in day 1, began to fall in day 3, and returned to normal in day 5. There was significant difference in blood glucose level between hemorrhagic stroke and nonhemorrhagic stroke (p < 0.005), there was correlation between hyperglycemia and length of treatment (for hemorrhagic stroke, p < 0.037 whereas for nonhemorrhagic stroke, p < 0.010), there was correlation between hyperglycemia and mortality (for hemorrhagic stroke, p < 0.010 whereas for nonhemorrhagic stroke, p < 0.001). Conclusion: Hyperglycemia in acute stroke (hemorrhagic and nonhemorrhagic) will cause longer treatment and higher mortality rate. Latar belakang : Stroke merupakan salah satu penyakit kardiovaskular yang perlu mendapat perhatian oleh karena penyebab kematian yang sering dijumpai dan menimbulkan kecacatan jangka panjang. Upaya ideal untuk menghadapi masalah stroke adalah dengan pencegahan faktor risiko , dari berbagai faktor tersebut hiperglikemia merupakan faktor yang penting untuk terjadinya stroke. Hiperglikemia yang terjadi bisa timbul pada penderita yang tidak menderita atau tidak mempunyai riwayat diabetes mellitus sebelumnya. Ttfuan : Mengetahui pola kadar glukosa sewaktu pada stroke akut, korelasi hiperglikemia dengan lama rawat, kematian, dan jumlah lokasi stroke yang terkena. Bahan dan cara kerja : Rancangan penelitian prospective cross sectional , penelitian dilakukan terhadap penderita stroke akut yang dirawat di bangsal syaraf RSDK. Data yang diambil glukosa darah sewaktu hari LIII,V, GD I/ II, Al C. Hasil : Didapatkan 66 penderita stroke akut ( berdasarkan CT scan ) : 27 penderita perdarahan ( S-P ), 39 penderita non perdarahan ( S-NP ), jenis kelamin 27 pria, 39 wanita, rerata umur S-P 54,44 ±11,22, .S-NP 59,05 ± 11,65 th. Glukosa darah sewaktu meningkat pada hari I, mulai turun pada hari 3, dan normal hari 5. Didapat perbedaan bermakna antara kadar glukosa darah S-P dan S-NP ( p < 0,005 ), adanya korelasi antara hiperglikemia dengan lama rawat ( S-P p < 0,037, S-NP p < 0,010 ), korelasi hiperglikemia dengan kematian ( S-P p < 0,010, S-NP p < 0,001 ). Kesimpulan : Hiperglikemia yang terjadi pada stroke akut ( perdarahan dan non perdarahan ) akan menyebabkan lebih lama masa perawatan dan risiko kematian.