PERBEDAAN EFEK KARDIOVASKULER PADA ANESTESI INHALASI ENFLURAN ANTARA TEKNIK MEDIUM-FLOW DAN HIGH-FLOW SEMICLOSED SYSTEM

Abstract

Background: The anesthesia procedure may effects to all system of the body, including cardiovascular. Enflurane inhalation is one of common used drugs in general anesthesia with high-flow even very high-flow semiclosed system technique. The objective of this study was proving that medium-flow semiclosed system technique can be use safely without decreasing the quality of anesthesia. Methods: This was an observational analytic study using cross sectional design, with 44 samples of medical records of patients experiencing elective surgery with general anesthesia at Kariadi Hospital Semarang. The sample fullfilled inclussion criterias; 16-40 years old, Body Mass Index (BMI) 20-25 kg/m2, status of physical of American Society Of Anesthesiologist (ASA) I-II, surgery duration 1-3 hours. From 44 samples divided into two groups. Group I treated with inhalation general anaesthesia with medium-flow semiclosed system using N2O 50 % in O2 with 2 l/minute fresh gas flow (FGF) acceleration and enflurane. Group 2 conducted inhalation general anesthesia with high-flow semiclosed system using N2O 50 % in O2 with 6 l/minute (FGF) acceleration and enflurane. The data was analysed using Kolmogorov-Smirnov and Independent T-test. Results: There was no significant difference in cardiovascular effects on enflurane anesthetic medium-flow and high-flow semiclosed system. The systolic and diastolic pressure, as well as the pulse at 15, 30, 45 and 60 minutes have p>0,05. At 60 minutes, the diastolic pressure between groups have a significant different (p<0,05), the diastolic in medium-flow was higher than high-flow technique. Conclusion: There was no difference of cardiovascular effect on enflurane anaesthetic between medium-flow and high-flow semiclosed system technique.